Analyzing Retrophin (RTRX) and Regenxbio (RGNX)

Retrophin (NASDAQ: RTRX) and Regenxbio (NASDAQ:RGNX) are both small-cap healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their valuation, analyst recommendations, institutional ownership, profitability, risk, earnings and dividends.

Insider & Institutional Ownership

68.7% of Regenxbio shares are held by institutional investors. 2.9% of Retrophin shares are held by company insiders. Comparatively, 17.0% of Regenxbio shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Analyst Ratings

This is a summary of current ratings and price targets for Retrophin and Regenxbio, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Retrophin 0 0 2 0 3.00
Regenxbio 0 0 6 0 3.00

Retrophin currently has a consensus target price of $44.00, suggesting a potential upside of 89.82%. Regenxbio has a consensus target price of $43.17, suggesting a potential upside of 54.17%. Given Retrophin’s higher possible upside, equities analysts plainly believe Retrophin is more favorable than Regenxbio.

Valuation & Earnings

This table compares Retrophin and Regenxbio’s revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Retrophin $133.59 million 6.82 -$47.90 million ($1.32) -17.56
Regenxbio $4.59 million 190.02 -$62.96 million ($2.71) -10.33

Retrophin has higher revenue and earnings than Regenxbio. Retrophin is trading at a lower price-to-earnings ratio than Regenxbio, indicating that it is currently the more affordable of the two stocks.


This table compares Retrophin and Regenxbio’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Retrophin -33.79% -10.13% -5.94%
Regenxbio -764.06% -39.33% -36.98%


Retrophin beats Regenxbio on 7 of the 12 factors compared between the two stocks.

Retrophin Company Profile

Retrophin, Inc. is a biopharmaceutical company. The Company is focused on the development, acquisition and commercialization of therapies for the treatment of serious, catastrophic or rare diseases. The Company sells three products, including Chenodal (chenodeoxycholic acid), Cholbam (cholic acid) and Thiola (tiopronin). Its Chenodal is approved in the United States for the treatment of patients suffering from gallstones in whom surgery poses an unacceptable health risk due to disease or advanced age. Chenodal has also been care for cerebrotendinous xanthomatosis (CTX) patients. Its Cholbam is approved in the United States for the treatment of bile acid synthesis disorders due to single enzyme defects and is further indicated for adjunctive treatment of patients with peroxisomal disorders. Its Thiola is approved in the United States for the prevention of cystine (kidney) stone formation in patients with severe homozygous cystinuria.

Regenxbio Company Profile

REGENXBIO Inc. is a clinical-stage biotechnology company. The Company’s gene therapy product candidates are designed to deliver genes to cells to address genetic defects or to enable cells in the body to produce therapeutic proteins or antibodies that are intended to impact disease. The Company develops products candidates across the therapeutic areas of metabolic, neurodegenerative and retinal diseases. Its product candidate, RGX-314, is meant for the treatment of wet age-related macular degeneration (wet AMD). Its product candidate, RGX-501, is meant for the treatment of homozygous familial hypercholesterolemia (HoFH). It is also developing product candidates, such as RGX-111 and RGX-121, to address the neurological symptoms of two severe genetic lysosomal storage diseases, Mucopolysaccharidosis Type I (MPS I) and Mucopolysaccharidosis Type II (MPS II), respectively. Its product candidates utilize viral vectors from its gene delivery platform, NAV Technology Platform.

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