Comparing VBI Vaccines (VBIV) and SIGA Technologies (OTCMKTS:SIGA)

SIGA Technologies (OTCMKTS: SIGA) and VBI Vaccines (NASDAQ:VBIV) are both small-cap medical companies, but which is the better stock? We will compare the two businesses based on the strength of their risk, earnings, valuation, profitability, dividends, institutional ownership and analyst recommendations.


This table compares SIGA Technologies and VBI Vaccines’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
SIGA Technologies -201.85% N/A -23.22%
VBI Vaccines -4,463.06% -49.17% -37.55%

Analyst Recommendations

This is a summary of recent ratings and price targets for SIGA Technologies and VBI Vaccines, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SIGA Technologies 0 0 0 0 N/A
VBI Vaccines 0 0 3 0 3.00

VBI Vaccines has a consensus target price of $10.50, suggesting a potential upside of 135.43%. Given VBI Vaccines’ higher probable upside, analysts plainly believe VBI Vaccines is more favorable than SIGA Technologies.

Valuation and Earnings

This table compares SIGA Technologies and VBI Vaccines’ top-line revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
SIGA Technologies $14.99 million 26.11 -$39.69 million ($0.53) -9.36
VBI Vaccines $550,000.00 517.44 -$23.20 million N/A N/A

VBI Vaccines has lower revenue, but higher earnings than SIGA Technologies.

Institutional and Insider Ownership

6.7% of SIGA Technologies shares are owned by institutional investors. Comparatively, 20.9% of VBI Vaccines shares are owned by institutional investors. 4.7% of SIGA Technologies shares are owned by company insiders. Comparatively, 54.5% of VBI Vaccines shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Risk and Volatility

SIGA Technologies has a beta of 0.73, suggesting that its share price is 27% less volatile than the S&P 500. Comparatively, VBI Vaccines has a beta of 4.08, suggesting that its share price is 308% more volatile than the S&P 500.


VBI Vaccines beats SIGA Technologies on 7 of the 11 factors compared between the two stocks.

SIGA Technologies Company Profile

SIGA Technologies, Inc. is engaged in the development and commercialization of solutions for various unmet medical needs and biothreats. The Company’s lead product is TPOXX, an orally administered antiviral drug that targets orthopoxviruses infections. TPOXX is a small-molecule drug delivered to the Strategic Stockpile under the Project BioShield Act of 2004 (Project BioShield). TPOXX is an investigational product that is not approved by the United States Food and Drug Administration (FDA) as a treatment of smallpox or any other indication. The Company relies on and uses third parties known as contract manufacturing organizations (CMOs) to procure commercial raw materials and supplies, and to manufacture TPOXX. The Company identified a lead pre-clinical drug candidate with activity against four serotypes of the virus and which has shown efficacy in a murine model of disease.

VBI Vaccines Company Profile

VBI Vaccines Inc., formerly SciVac Therapeutics Inc., is a biotechnology company. The Company is engaged in developing various technologies that focus on vaccine protection. It has developed an enveloped virus like particle (eVLP) vaccine platform that allows for the design of enveloped VLP vaccines. It is involved in various projects related to human cytomegalovirus (CMV) and other antigens. It is engaged in developing an experimental CMV vaccine using its eVLP vaccine platform. The vaccine is based on the CMV glycoprotein B antigen and is adjuvanted with aluminum phosphate. The eVLP vaccine technology allows for the expression of envelope glyco-proteins within a lipid-bilayer membrane of a VLP. It is developing a therapeutic vaccine candidate for glioblastoma multiforme (GBM). It is developing a vaccine to prevent respiratory syncytial virus (RSV) infection. It also offers Sci-B-Vac, which is a third-generation hepatitis B vaccine.

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