Reviewing G1 Therapeutics (GTHX) and Kindred Biosciences (KIN)

G1 Therapeutics (NASDAQ: GTHX) and Kindred Biosciences (NASDAQ:KIN) are both small-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their profitability, institutional ownership, dividends, valuation, analyst recommendations, earnings and risk.

Valuation & Earnings

This table compares G1 Therapeutics and Kindred Biosciences’ top-line revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
G1 Therapeutics N/A N/A N/A ($2.15) -11.12
Kindred Biosciences N/A N/A -$22.49 million ($1.17) -7.48

G1 Therapeutics is trading at a lower price-to-earnings ratio than Kindred Biosciences, indicating that it is currently the more affordable of the two stocks.

Insider and Institutional Ownership

43.3% of G1 Therapeutics shares are held by institutional investors. Comparatively, 66.8% of Kindred Biosciences shares are held by institutional investors. 19.1% of Kindred Biosciences shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Analyst Recommendations

This is a summary of recent ratings and target prices for G1 Therapeutics and Kindred Biosciences, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
G1 Therapeutics 0 0 5 0 3.00
Kindred Biosciences 0 2 4 0 2.67

G1 Therapeutics presently has a consensus price target of $31.40, suggesting a potential upside of 31.33%. Kindred Biosciences has a consensus price target of $9.90, suggesting a potential upside of 13.14%. Given G1 Therapeutics’ stronger consensus rating and higher possible upside, research analysts clearly believe G1 Therapeutics is more favorable than Kindred Biosciences.


This table compares G1 Therapeutics and Kindred Biosciences’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
G1 Therapeutics N/A N/A N/A
Kindred Biosciences N/A -36.18% -34.66%


G1 Therapeutics beats Kindred Biosciences on 5 of the 9 factors compared between the two stocks.

G1 Therapeutics Company Profile

G1 Therapeutics, Inc. is a United States-based clinical-stage biopharmaceutical company. The Company is engaged in developing small-molecule therapies for the treatment of cancer. Its two clinical-stage candidates are trilaciclib (G1T28) and G1T38, which are potent, selective inhibitors of the validated kinase targets CDK4/6. Trilaciclib and G1T38 are designed to be combined and enhance the anti-tumor activity of current therapies. It is also developing G1T48, an oral selective estrogen receptor degrader (SERD) for the treatment of breast cancer. The Company is evaluating trilaciclib in three Phase II clinical trials. G1T38 is being evaluated in combination with Faslodex in a Phase I b/II a trial for patients with estrogen receptor-positive, HER2-negative breast cancer.

Kindred Biosciences Company Profile

Kindred Biosciences, Inc. is a development-stage biopharmaceutical company. The Company is focused on developing therapies for pets. The Company’s product pipeline consists of small molecules and biologics for a range of indications in dogs, cats and horses. The Company is developing product candidates for over 20 indications and focused on small molecule products and canine and feline biologics products. The Company is developing antibodies that targets canine Interleukin 17A (IL-17a), Interleukin 4A (IL-4Ra), Interleukin 3 (IL-3), CD-20, Immunoglobulin E (IgE), tumor necrosis factors (TNF) and other validated targets. The Company’s lead product candidates are Zimeta, which is indicated for the treatment of fever in horses, and KIND-010 for management of weight loss in cats. The Company’s other product candidates include KIND-010, KIND-014, KIND-015, KIND-510, KIND-502, KIND-0888, KIND-509, and several antibodies that target cytokines involved in atopic dermatitis.

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