Covance (NYSE:CVD) vs. Aptose Biosciences (APTO) Head to Head Contrast

Covance (NYSE: CVD) and Aptose Biosciences (NASDAQ:APTO) are both biotechnology & medical research – nec companies, but which is the better business? We will compare the two businesses based on the strength of their analyst recommendations, valuation, profitability, risk, dividends, earnings and institutional ownership.


This table compares Covance and Aptose Biosciences’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Covance 7.70% 12.64% 8.17%
Aptose Biosciences N/A -129.12% -111.84%

Valuation and Earnings

This table compares Covance and Aptose Biosciences’ gross revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Covance N/A N/A N/A $3.24 33.05
Aptose Biosciences N/A N/A -$14.06 million ($0.60) -4.50

Aptose Biosciences is trading at a lower price-to-earnings ratio than Covance, indicating that it is currently the more affordable of the two stocks.

Institutional and Insider Ownership

0.9% of Aptose Biosciences shares are held by institutional investors. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Analyst Recommendations

This is a summary of current ratings and target prices for Covance and Aptose Biosciences, as provided by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Covance 0 0 0 0 N/A
Aptose Biosciences 0 1 3 0 2.75

Aptose Biosciences has a consensus target price of $6.00, suggesting a potential upside of 122.22%. Given Aptose Biosciences’ higher possible upside, analysts plainly believe Aptose Biosciences is more favorable than Covance.


Covance beats Aptose Biosciences on 5 of the 8 factors compared between the two stocks.

Covance Company Profile

Covance Inc. is engaged in drug development services. The Company provides a range of early-stage and late-stage product development services to the pharmaceutical and biotechnology industries. The Company also provides laboratory testing services to the chemical, agrochemical and food industries. The Company operates in two segments: early development services, and late-stage development services. The early development services include lead optimization services, preclinical services and clinical pharmacology services. The late-stage development services include central laboratory, Phase II-IV clinical development, and market access services.

Aptose Biosciences Company Profile

Aptose Biosciences Inc. (Aptose) is a clinical-stage biotechnology company. The Company is engaged in the development of anticancer drugs that target specific epigenetic processes and signal transduction abnormalities that underlie a particular life-threatening malignancy. Its product pipeline includes cancer drug candidates that exert activity as stand-alone agents and that enhance the activities of other anticancer agents without causing overlapping toxicities. The Company develops therapeutics focused on epigenetic processes and signal transduction abnormalities at the edge of cancer research, coupled with companion diagnostics to identify the optimal patient population for its products. The Company’s APTO-253 is a small molecule that can induce expression of the genes that codes for the Kruppel-like factor 4 (KLF4) master transcription factor and the p21 cell cycle inhibitor protein.

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