Cellectis (CLLS) and Zynerba Pharmaceuticals (ZYNE) Financial Contrast

Cellectis (NASDAQ: CLLS) and Zynerba Pharmaceuticals (NASDAQ:ZYNE) are both small-cap healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their valuation, earnings, institutional ownership, analyst recommendations, profitability, dividends and risk.

Analyst Ratings

This is a summary of current recommendations and price targets for Cellectis and Zynerba Pharmaceuticals, as provided by MarketBeat.com.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cellectis 0 1 5 0 2.83
Zynerba Pharmaceuticals 0 4 7 0 2.64

Cellectis currently has a consensus target price of $39.83, suggesting a potential upside of 22.00%. Zynerba Pharmaceuticals has a consensus target price of $18.15, suggesting a potential upside of 62.93%. Given Zynerba Pharmaceuticals’ higher possible upside, analysts clearly believe Zynerba Pharmaceuticals is more favorable than Cellectis.

Valuation & Earnings

This table compares Cellectis and Zynerba Pharmaceuticals’ gross revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Cellectis $56.46 million 20.78 -$67.25 million ($2.81) -11.62
Zynerba Pharmaceuticals $10,000.00 15,094.70 -$23.38 million ($2.59) -4.30

Zynerba Pharmaceuticals has lower revenue, but higher earnings than Cellectis. Cellectis is trading at a lower price-to-earnings ratio than Zynerba Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

Profitability

This table compares Cellectis and Zynerba Pharmaceuticals’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Cellectis -217.25% -30.66% -25.66%
Zynerba Pharmaceuticals N/A -50.64% -45.05%

Institutional and Insider Ownership

16.4% of Cellectis shares are held by institutional investors. Comparatively, 26.2% of Zynerba Pharmaceuticals shares are held by institutional investors. 16.4% of Cellectis shares are held by company insiders. Comparatively, 9.9% of Zynerba Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Summary

Zynerba Pharmaceuticals beats Cellectis on 8 of the 13 factors compared between the two stocks.

Cellectis Company Profile

Cellectis SA is a France-based company active in the field of genome engineering and genomic surgery. The Company specializes in the research, development and commercialization of rational genome engineering technologies. It has developed an expertise in combining meganucleases with engineered targeting Deoxyribonucleic Acid (DNA) matrices into Meganuclease Recombination Systems (MRS), used for gene excision, correction or replacement. The Company also offers rational inverse genetics and targeting recombination tools. Cellectis SA markets its technologies mainly for use in the research field, in pharmaceutical drug discovery programs, in the agronomics, bioproduction and biotherapeutics fields. Cellectis SA operates several subsidiaries. The Company operates in France and the United States, among others.

Zynerba Pharmaceuticals Company Profile

Zynerba Pharmaceuticals, Inc. is a specialty pharmaceutical company. The Company is engaged in developing and commercializing transdermal synthetic cannabinoid treatments for patients with high unmet needs. Its development pipeline includes two product candidates: ZYN002 and ZYN001. ZYN002 is a synthetic cannabidiol (CBD), which is a non-psychoactive cannabinoid, formulated as a patent-protected permeation-enhanced gel for transdermal delivery through the skin and into the circulatory system. ZYN002 is in Phase II clinical development in patients with refractory epilepsy, in patients with osteoarthritis of the knee, as well as in patients with Fragile X syndrome. ZYN001 is a pro-drug of tetrahydrocannabinol (THC) that enables transdermal delivery through the skin and into the circulatory system through a patch. ZYN001 is targeting two pain indications, fibromyalgia and peripheral neuropathic pain.

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