Head to Head Review: MKS Instruments (MKSI) & International Isotopes (INIS)

MKS Instruments (NASDAQ:MKSI) and International Isotopes (OTCMKTS:INIS) are both computer and technology companies, but which is the superior investment? We will contrast the two companies based on the strength of their profitability, institutional ownership, risk, dividends, analyst recommendations, earnings and valuation.

Insider & Institutional Ownership

90.1% of MKS Instruments shares are owned by institutional investors. 1.7% of MKS Instruments shares are owned by insiders. Comparatively, 11.9% of International Isotopes shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Valuation and Earnings

This table compares MKS Instruments and International Isotopes’ revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
MKS Instruments $1.92 billion 2.16 $339.13 million $5.96 12.69
International Isotopes $7.42 million 4.45 -$3.75 million N/A N/A

MKS Instruments has higher revenue and earnings than International Isotopes.

Analyst Recommendations

This is a breakdown of current ratings and target prices for MKS Instruments and International Isotopes, as provided by MarketBeat.com.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
MKS Instruments 0 0 7 0 3.00
International Isotopes 0 0 0 0 N/A

MKS Instruments currently has a consensus target price of $116.50, indicating a potential upside of 54.08%. Given MKS Instruments’ higher possible upside, equities analysts plainly believe MKS Instruments is more favorable than International Isotopes.

Volatility and Risk

MKS Instruments has a beta of 0.88, indicating that its share price is 12% less volatile than the S&P 500. Comparatively, International Isotopes has a beta of -0.25, indicating that its share price is 125% less volatile than the S&P 500.


MKS Instruments pays an annual dividend of $0.80 per share and has a dividend yield of 1.1%. International Isotopes does not pay a dividend. MKS Instruments pays out 13.4% of its earnings in the form of a dividend. MKS Instruments has raised its dividend for 6 consecutive years.


This table compares MKS Instruments and International Isotopes’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
MKS Instruments 18.76% 25.57% 17.58%
International Isotopes -29.66% -404.24% -21.40%


MKS Instruments beats International Isotopes on 11 of the 14 factors compared between the two stocks.

MKS Instruments Company Profile

MKS Instruments, Inc. provides instruments, subsystems, and process control solutions that measure, control, power, deliver, monitor, and analyze critical parameters of manufacturing processes worldwide. The company operates through two segments, Vacuum & Analysis and Light & Motion. The Vacuum & Analysis segment provides analytical and control solutions products, including gas analyzers, automation control products, I/O modules, automation software, and precision machined components and electromechanical assemblies; and materials delivery solutions products comprising flow and valve technologies, as well as integrated pressure measurement and control subsystems to provide customers with precise control capabilities that are optimized for a given application. It also offers power delivery, plasma, and reactive gas generation products used in semiconductor and other thin film applications, and in medical imaging equipment applications; and direct and indirect pressure measurement and integrated process solutions. The Light & Motion segment offers lasers and laser-based systems, including lasers and amplifiers, fiber lasers, diode-pumped solid-state lasers, high-energy pulsed lasers, and tunable lasers, as well as accessories; optics products, such as precision optics, thin-film filters and coatings, replicated mirrors, and ruled and holographic diffraction gratings; and photonics products comprising optical components, vibration, lens assemblies, and isolation solutions, as well as three-dimensional non-contact measurement sensors and equipment. It markets and sells its products and services through global direct sales organization, independent distributors and sales representatives, Websites, and product catalogs. The company was founded in 1961 and is headquartered in Andover, Massachusetts.

International Isotopes Company Profile

International Isotopes, Inc. manufactures and sells nuclear medicine calibration and reference standards, cobalt teletherapy sources, and radioisotopes and radiochemicals for medical research, pharmacy compounding, and clinical applications. The company operates in six segments: Nuclear Medicine Standards, Cobalt Products, Radiochemical Products, Fluorine Products, Radiological Services, and Transportation. The Nuclear Medicine Standards segment manufactures sources and standards associated with single photon emission computed tomography imaging, patient positioning, and calibration or operational testing of dose measuring equipment for the nuclear pharmacy industry. It offers flood sources, dose calibrators, rod sources, flexible and rigid rulers, spot markers, pen point markers, and various specialty design items. The Cobalt Products segment produces bulk cobalt; fabricates cobalt capsules for radiation therapy or various industrial applications; and recycles expended cobalt sources. The Radiochemical Products segment produces and distributes various isotopically pure radiochemicals for medical, industrial, and research applications. It provides iodine-131 radiochemical for use in the treatment and diagnosis of diseases of the thyroid gland, such as graves' disease, thyroid cancer, and hyperthyroidism, as well as for breast, lung, prostate, and ovarian cancers. The Fluorine Products segment offers products that are used to support the production and sale of gases produced using its fluorine extraction process. The Radiological Services segment decommissions disused irradiation units, performs sealed source exchanges in irradiation and therapy units, and processes gemstones. The Transportation segment provides transportation services for hazardous and non-hazardous cargo materials. The company sells its products directly to end users and distributors. International Isotopes, Inc. was founded in 1995 and is headquartered in Idaho Falls, Idaho.

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